The strand that underlies my work to date is a fascination with patterns and processes in nature.
As a child I remember walking through woods in the UK and being fascinated by the diversity of plants, insects and birds, and how these all interacted and seemingly depended on one another. I took a Marine Biology with Applied Zoology undergraduate degree (at the University of North Wales in the UK) – this was a integrative whole organism based degree with a heavy ecological focus. It was in the second year that I properly encountered the subject of evolutionary biology — I distinctly remember reading ‘The Selfish Gene’ by Richard Dawkins. The attraction of evolution for me was a system of thinking that put the diverse array of facts and observations concerning the natural world into perspective – a system that (sometimes) made sense of the natural world. I then moved onto research at the University of Leicester (UK) looking at the genetics of Tuberculosis, and it was here that I was introduced to, and learnt the foundations of, microbiology and molecular biology. After this I was fortunate to work toward a PhD under the guidance of Prof Austin Burt at Imperial College. The work examined the ecology and evolution of selfish genes. From here I gained a post-doctoral position at the NERC Centre for Population Biology, also based at Imperial College, initially under Prof John Lawton, and then Prof Charles Godfray, where I used yeast as model systems to conduct experimental evolution to test ideas about the maintenance of sex. From here I moved to my Faculty position at the University of Auckland. I now am based back in the UK at the University of Lincoln, but also retain a fractional position at the University of Auckland.
In the context of cross species interaction, my research interests are focused around molecular aspects of communication. I am a plant biochemist by trade and my studies ventured from legume-rhizobia symbiosis (MSc equiv. at the Max-Planck Insitute for Molecular Plant Physiology in Potsdam, Germany) to flavour-related volatiles in kiwi fruit (PhD in Chemistry, Plant and Food Research and University of Auckland, Auckland, New Zealand).
At no point I expected finding final answers doing research but stimulation to raise ever new questions. This, has not only led to an exciting journey across disciplines and countries but also across organisms. Yeast is a great model for exploring the origin of cellular life, diversity and of course chemical interaction.
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For as long as I can remember I have been fascinated with the natural world and the organisms inhabiting it. I began my studies at the University of Auckland as an undergraduate with a keen interest in conservation biology and ecology. This quickly grew to include population and evolutionary genetics which are now a large focus of my research. As part of my Masters research I tested hypotheses of the evolutionary relationships within an order of the Bryozoa (Cheilostomata) that were based on morphological evidence. By using DNA sequence data and phylogenetic reconstructions and topology testing I was able to provide evidence to support a number of these hypotheses. This solidified my passion for using genetics as a tool in population and evolutionary studies. I am now completing my PhD in the Goddard lab focusing on the fermenting yeast Saccharomyces cerevisiae. It has recently been shown that New Zealand has a genetically distinct population of S. cerevisiae and this research aims to describe and explain its population structure and determine if some of these New Zealand isolates can provide unique and desirable characteristics for winemaking.
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I have always been curious about ‘how stuff works’, a curiosity that led me to study Science at University. Since graduating, I have spent time working in a number of research labs before returning to the School of Biological Sciences, University of Auckland.
In Richard Gardner’s lab I spent some years working on yeast genes important for winemaking and wine flavour (specifically the varietal thiols in Sauvignon Blanc) and more recently, on breeding improved Saccharomyces cerevisiae strains for winemaking.
Since joining the Goddard lab in 2010, I have been involved in conducting & supporting the research efforts of the lab as part of the Sauvignon Blanc Research Programme. In 2011, much effort was devoted to a rigorous sampling of the yeasts associated with Sauvignon Blanc vineyards around New Zealand.
Currently, my main projects are:
1. The fit between yeast and juice (examining if S. cerevisiae exhibit strain differences in their preferences for nutrient sources during fermentation, and if so, might this be used to improve yeast selection for winemaking).
2. The adaptation of yeasts to ferment conditions (testing if fitness of S. cerevisiae can be improved to ensure successful completion of winemaking ferments).
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I received my BSc, PgDipSci and MSc from the University of Auckland majoring in Biological sciences. I joined the Goddard group in 2010 to pursue research of community biogeography and ecology of non-Saccharomyces yeast associated with vineyards and native areas in New Zealand.
+64 9 3737599 x81238
I received my BSc/BA conjoint degrees from the University of Auckland, majoring in biology, philosophy and economics, followed by a PGDipSci in 2012. My studies in science have focussed on molecular biology and on the side I have delved into the metaphysical implications. A related question concerns how the molecular events underlying adaptation are linked to larger evolutionary patterns such as convergence in organismal form. I’ve been inspired by the work of researchers such as Simon Conway-Morris who have explored the relations between biological trends, philosophy, and theology.
My MSc project in the Goddard lab involves bioinformatic analysis of a previous experimental evolution project using the yeast S. cerevisiae. I am applying next generation sequencing of population genomes to discover adaptations which occurred in sexual and asexual strains, and the molecular differences correlated with changes in meiotic recombination and gene-flow between environments. This should contribute to wider debates about the role of sex and migration in the adaptation of eukaryotes to complex environments.
+64 9 3737599 x81238
Henry de Malmanche